2Y3P

Crystal structure of N-terminal domain of GyrA with the antibiotic simocyclinone D8

Replaces:  2WL2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA GYRASE SUBUNIT A	polymer	522	58623.0	2	UniProt (P0AES5) Pfam (PF00521)	ESCHERICHIA COLI	GYRA
2	C, D, F, G (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG) PubChem (888)
3	E, H (A, B)	SIMOCYCLINONE D8	non-polymer		932.3	2	Chemie (SM8) PubChem (54696356) PubChem (54676044) PubChem (54736483) PubChem (54734246) PubChem (71480057) PubChem (76168195) PubChem (131852254) PubChem (162982249) PubChem (162982242) PubChem (162982244) PubChem (170924213) PubChem (171157404) PubChem (162982243) PubChem (162982245) PubChem (162982246) PubChem (162982247) PubChem (162982248) PubChem (163185745) PubChem (167994884)
4	I, J (A, B)	water	water		18.0	96	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	117246.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1961.8
All*	Total formula weight	119207.8

*Water molecules are not included.