2X23
crystal structure of M. tuberculosis InhA inhibited by PT70
Summary for 2X23
Entry DOI | 10.2210/pdb2x23/pdb |
Related | 1BVR 1ENY 1ENZ 1P44 1P45 1ZID 2AQI 2AQK 2B35 2B36 2B37 2H7I 2H7M 2H7P 2NV6 2X22 |
Descriptor | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 5-HEXYL-2-(2-METHYLPHENOXY)PHENOL, ... (5 entities in total) |
Functional Keywords | fatty acid biosynthesis, oxidoreductase, lipid synthesis, antibiotic resistance |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 4 |
Total formula weight | 118088.53 |
Authors | Luckner, S.R.,Liu, N.,am Ende, C.W.,Tonge, P.J.,Kisker, C. (deposition date: 2010-01-10, release date: 2010-03-02, Last modification date: 2024-05-08) |
Primary citation | Luckner, S.R.,Liu, N.,Am Ende, C.W.,Tonge, P.J.,Kisker, C. A Slow, Tight Binding Inhibitor of Inha, the Enoyl-Acyl Carrier Protein Reductase from Mycobacterium Tuberculosis. J.Biol.Chem., 285:14330-, 2010 Cited by PubMed: 20200152DOI: 10.1074/JBC.M109.090373 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.807 Å) |
Structure validation
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