2X10

Crystal structure of the complete EphA2 ectodomain

Summary for 2X10

Entry DOI	10.2210/pdb2x10/pdb
Related	1MQB 2X11
Descriptor	EPHRIN TYPE-A RECEPTOR 2, CHLORIDE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	transferase, angiogenesis, kinase, cataract, receptor, apoptosis, glycoprotein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	60678.61
Authors	Seiradake, E.,Harlos, K.,Sutton, G.,Aricescu, A.R.,Jones, E.Y. (deposition date: 2009-12-21, release date: 2010-03-16, Last modification date: 2023-12-20)
Primary citation	Seiradake, E.,Harlos, K.,Sutton, G.,Aricescu, A.R.,Jones, E.Y. An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly Nat.Struct.Mol.Biol., 17:398-, 2010 Cited by PubMed: 20228801 DOI: 10.1038/NSMB.1782 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation