2WVR

Human Cdt1:Geminin complex

Summary for 2WVR

• Entry DOI: 10.2210/pdb2wvr/pdb
• Related: 1T6F 1UII
• Descriptor: GEMININ, DNA REPLICATION FACTOR CDT1 (2 entities in total)
• Functional Keywords: replication, dna replication license, dna replication inhibitor, phosphoprotein, ubl conjugation, dna replication, dna-binding, polymorphism, proto-oncogene, nucleus, cell cycle, acetylation, coiled coil
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: Q9H211
• Total number of polymer chains: 3
• Total formula weight: 107733.75

Authors

De Marco, V.,Perrakis, A. (deposition date: 2009-10-19, release date: 2009-10-27, Last modification date: 2011-07-13)

• Primary citation: De Marco, V.,Gillespie, P.J.,Li, A.,Karantzelis, N.,Christodoulou, E.,Klompmaker, R.,Van Gerwen, S.,Fish, A.,Petoukhov, M.V.,Iliou, M.S.,Lygerou, Z.,Medema, R.H.,Blow, J.J.,Svergun, D.I.,Taraviras, S.,Perrakis, A.; Quaternary Structure of the Human Cdt1-Geminin Complex Regulates DNA Replication Licensing.; Proc.Natl.Acad.Sci.USA, 106:19807-, 2009; PubMed: 19906994; DOI: 10.1073/PNAS.0905281106

Experimental method

X-RAY DIFFRACTION (3.3 Å)