2WNG

complete extracellular structure of human signal regulatory protein (SIRP) alpha

2WNG の概要

• エントリーDOI: 10.2210/pdb2wng/pdb
• 関連するPDBエントリー: 2JJS 2JJT 2UV3
• 分子名称: TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: signal regulatory protein alpha, immunoglobulin superfamily, phosphoprotein, disulfide bond, paired receptor, alternative splicing, immunoglobulin domain, sirp, cd47, sirpa, membrane, sh3-binding, polymorphism, glycoprotein, transmembrane, cell adhesion
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36425.54

構造登録者

Hatherley, D.,Graham, S.C.,Harlos, K.,Stuart, D.I.,Barclay, A.N. (登録日: 2009-07-09, 公開日: 2009-07-21, 最終更新日: 2023-12-13)

• 主引用文献: Hatherley, D.,Graham, S.C.,Harlos, K.,Stuart, D.I.,Barclay, A.N.; Structure of Signal-Regulatory Protein Alpha: A Link to Antigen Receptor Evolution.; J.Biol.Chem., 284:26613-, 2009; PubMed: 19628875; DOI: 10.1074/JBC.M109.017566

実験手法

X-RAY DIFFRACTION (2.49 Å)