2WKO

Structure of metal loaded Pathogenic SOD1 Mutant G93A.

2WKO の概要

• エントリーDOI: 10.2210/pdb2wko/pdb
• 関連するPDBエントリー: 1AZV 1BA9 1DSW 1FUN 1HL4 1HL5 1KMG 1L3N 1MFM 1N18 1N19 1OEZ 1OZT 1OZU 1P1V 1PTZ 1PU0 1RK7 1SOS 1SPD 1UXL 1UXM 2AF2 2C9S 2C9U 2C9V 2V0A 2VR6 2VR7 2VR8 3GZO 3GZP 3GZQ 4SOD
• 分子名称: SUPEROXIDE DISMUTASE [CU-ZN], COPPER (II) ION, ZINC ION, ... (6 entities in total)
• 機能のキーワード: amyotrophic lateral sclerosis, phosphoprotein, oxidoreductase, disease mutation, neurodegeneration, acetylation, antioxidant, metal-binding
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Cytoplasm: P00441 P00441
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32389.87

構造登録者

Antonyuk, S.V.,Galaleldeen, A.,Strange, R.,Whitson, L.,Narayana, N.,Taylor, A.,Schuermann, J.P.,Holloway, S.P.,Hasnain, S.S.,Hart, P.J. (登録日: 2009-06-16, 公開日: 2009-11-24, 最終更新日: 2023-12-13)

• 主引用文献: Galaleldeen, A.,Strange, R.W.,Whitson, L.J.,Antonyuk, S.V.,Narayana, N.,Taylor, A.B.,Schuermann, J.P.,Holloway, S.P.,Hasnain, S.S.,Hart, P.J.; Structural and Biophysical Properties of Metal-Free Pathogenic Sod1 Mutants A4V and G93A.; Arch.Biochem.Biophys., 492:40-, 2009; PubMed: 19800308; DOI: 10.1016/J.ABB.2009.09.020

実験手法

X-RAY DIFFRACTION (1.97 Å)