2W66

BtGH84 in complex with HQ602

Summary for 2W66

Entry DOI	10.2210/pdb2w66/pdb
Related	2CHN 2CHO 2J47 2J4G 2JIW 2VVN 2VVS 2VW3 2W4X 2W67
Descriptor	O-GLCNACASE BT_4395, N-[(3R,4S,5R,6R,7R)-3,5,6-trihydroxy-7-(hydroxymethyl)azepan-4-yl]acetamide, CALCIUM ION, ... (5 entities in total)
Functional Keywords	glycoside hydrolase, complex, hydrolase, inhibitor, glycosidase
Biological source	BACTEROIDES THETAIOTAOMICRON VPI-5482
Total number of polymer chains	2
Total formula weight	165365.06
Authors	He, Y.,Davies, G.J. (deposition date: 2008-12-17, release date: 2009-04-14, Last modification date: 2023-12-13)
Primary citation	Marcelo, F.,He, Y.,Yuzwa, S.A.,Nieto, L.,Jimenez-Barbero, J.,Sollogoub, M.,Vocadlo, D.J.,Davies, G.J.,Bleriot, Y. Molecular Basis for Inhibition of Gh84 Glycoside Hydrolases by Substituted Azepanes: Conformational Flexibility Enables Probing of Substrate Distortion. J.Am.Chem.Soc., 131:5390-, 2009 Cited by PubMed: 19331390 DOI: 10.1021/JA809776R PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.27 Å)

Structure validation