2W51

Human mesencephalic astrocyte-derived neurotrophic factor (MANF)

Summary for 2W51

• Entry DOI: 10.2210/pdb2w51/pdb
• Related: 2W50
• Descriptor: PROTEIN ARMET (1 entity in total)
• Functional Keywords: manf, cdnf, saposin, secreted, er stress, phosphoprotein, neurotrophic factor, sialic acid, glycoprotein, growth factor, hormone
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 18195.14

Authors

Parkash, V.,Lindholm, P.,Peranen, J.,Kalkkinen, N.,Oksanen, E.,Saarma, M.,Leppanen, V.M.,Goldman, A. (deposition date: 2008-12-03, release date: 2009-03-17, Last modification date: 2024-05-01)

• Primary citation: Parkash, V.,Lindholm, P.,Peranen, J.,Kalkkinen, N.,Oksanen, E.,Saarma, M.,Leppanen, V.M.,Goldman, A.; The Structure of the Conserved Neurotrophic Factors Manf and Cdnf Explains Why They are Bifunctional.; Protein Eng.Des.Sel., 22:233-241, 2009; PubMed: 19258449; DOI: 10.1093/PROTEIN/GZN080

Experimental method

X-RAY DIFFRACTION (2.8 Å)