2W50

N-terminal domain of human conserved dopamine neurotrophic factor (CDNF)

Summary for 2W50

• Entry DOI: 10.2210/pdb2w50/pdb
• Descriptor: ARMET-LIKE PROTEIN 1, PHOSPHATE ION (3 entities in total)
• Functional Keywords: manf, cdnf, saposin, secreted, er stress, alternative splicing, hormone, growth factor, neurotrophic factor
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 23881.43

Authors

Parkash, V.,Lindholm, P.,Peranen, J.,Kalkkinen, N.,Oksanen, E.,Saarma, M.,Leppanen, V.M.,Goldman, A. (deposition date: 2008-12-03, release date: 2009-03-17, Last modification date: 2019-05-08)

• Primary citation: Parkash, V.,Lindholm, P.,Peranen, J.,Kalkkinen, N.,Oksanen, E.,Saarma, M.,Leppanen, V.M.,Goldman, A.; The Structure of the Conserved Neurotrophic Factors Manf and Cdnf Explains Why They are Bifunctional.; Protein Eng.Des.Sel., 22:233-, 2009; PubMed: 19258449; DOI: 10.1093/PROTEIN/GZN080

Experimental method

X-RAY DIFFRACTION (1.6 Å)