2W0D
Does a Fast Nuclear Magnetic Resonance Spectroscopy- and X-Ray Crystallography Hybrid Approach Provide Reliable Structural Information of Ligand-Protein Complexes? A Case Study of Metalloproteinases.
Summary for 2W0D
Entry DOI | 10.2210/pdb2w0d/pdb |
Related | 1JIZ 1JK3 1OS2 1OS9 1RMZ 1ROS 1UTT 1UTZ 1Y93 1YCM 1Z3J |
Descriptor | MACROPHAGE METALLOELASTASE, ZINC ION, CALCIUM ION, ... (8 entities in total) |
Functional Keywords | glycoprotein, metal-binding, metalloprotease, secreted, hydrolase, hydroxamate, extracellular matrix, copd, mmp-12, zymogen |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 4 |
Total formula weight | 76337.88 |
Authors | Isaksson, J.,Nystrom, S.,Derbyshire, D.J.,Wallberg, H.,Agback, T.,Kovacs, H.,Bertini, I.,Felli, I.C. (deposition date: 2008-08-13, release date: 2009-03-03, Last modification date: 2024-05-01) |
Primary citation | Isaksson, J.,Nystrom, S.,Derbyshire, D.J.,Wallberg, H.,Agback, T.,Kovacs, H.,Bertini, I.,Felli, I.C. Does a Fast Nuclear Magnetic Resonance Spectroscopy- and X-Ray Crystallography Hybrid Approach Provide Reliable Structural Information of Ligand-Protein Complexes? a Case Study of Metalloproteinases. J.Med.Chem., 52:1712-, 2009 Cited by PubMed: 19239231DOI: 10.1021/JM801388Q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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