2VFA

Crystal structure of a chimera of Plasmodium falciparum and human hypoxanthine-guanine phosphoribosyl transferases

2VFA の概要

• エントリーDOI: 10.2210/pdb2vfa/pdb
• 関連するPDBエントリー: 1BZY 1CJB 1D6N 1HMP 1Z7G
• 分子名称: HYPOXANTHINE-GUANINE-XANTHINE PHOSPHORIBOSYLTRANSFERASE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, GUANOSINE-5'-MONOPHOSPHATE, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: hypoxanthine-guanine phosphoribosyl transferase (hgprt), purine salvage, disease mutation, glycosyltransferase, transferase, metal-binding, gout, chimera, magnesium
• 由来する生物種: PLASMODIUM FALCIPARUM; 詳細
• 細胞内の位置: Cytoplasm: P20035
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52584.45

構造登録者

Gayathri, P.,Selvi, T.S.,Subbayya, I.N.S.,Ashok, C.S.,Balaram, H.,Murthy, M.R.N. (登録日: 2007-11-02, 公開日: 2008-06-17, 最終更新日: 2023-12-13)

• 主引用文献: Gayathri, P.,Sujay Subbayya, I.N.,Ashok, C.S.,Selvi, T.S.,Balaram, H.,Murthy, M.R.N.; Crystal Structure of a Chimera of Human and Plasmodium Falciparum Hypoxanthine Guanine Phosphoribosyltransferases Provides Insights Into Oligomerization.; Proteins, 73:1010-, 2008; PubMed: 18536021; DOI: 10.1002/PROT.22129

実験手法

X-RAY DIFFRACTION (2.8 Å)