1Z7G
Free human HGPRT
Summary for 1Z7G
Entry DOI | 10.2210/pdb1z7g/pdb |
Related | 1BZY 1D6N 1HMP |
Descriptor | Hypoxanthine-guanine phosphoribosyltransferase (2 entities in total) |
Functional Keywords | flexibility, trans cis peptide bond isomerization, nucleotide binding, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00492 |
Total number of polymer chains | 4 |
Total formula weight | 97924.87 |
Authors | Keough, D.T.,Brereton, I.M.,de Jersey, J.,Guddat, L.W. (deposition date: 2005-03-24, release date: 2005-08-02, Last modification date: 2023-08-23) |
Primary citation | Keough, D.T.,Brereton, I.M.,de Jersey, J.,Guddat, L.W. The Crystal Structure of Free Human Hypoxanthine-guanine Phosphoribosyltransferase Reveals Extensive Conformational Plasticity Throughout the Catalytic Cycle J.Mol.Biol., 351:170-181, 2005 Cited by PubMed: 15990111DOI: 10.1016/j.jmb.2005.05.061 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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