2VE7

Crystal structure of a bonsai version of the human Ndc80 complex

Summary for 2VE7

Entry DOI	10.2210/pdb2ve7/pdb
Descriptor	KINETOCHORE PROTEIN HEC1, KINETOCHORE PROTEIN SPC25, KINETOCHORE PROTEIN NUF2, KINETOCHORE PROTEIN SPC24, GLYCEROL, ... (5 entities in total)
Functional Keywords	mitosis, centromere, cell cycle, microtubule, kinetochore, cell division, calponin homology
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Nucleus: Q9HBM1 Q8NBT2
Total number of polymer chains	4
Total formula weight	131061.84
Authors	Ciferri, C.,Pasqualato, S.,Dos Reis, G.,Screpanti, E.,Maiolica, A.,Polka, J.,De Luca, J.G.,De Wulf, P.,Salek, M.,Rappsilber, J.,Moores, C.A.,Salmon, E.D.,Musacchio, A. (deposition date: 2007-10-17, release date: 2008-05-13, Last modification date: 2022-05-04)
Primary citation	Ciferri, C.,Pasqualato, S.,Screpanti, E.,Varetti, G.,Santaguida, S.,Dos Reis, G.,Maiolica, A.,Polka, J.,De Luca, J.G.,De Wulf, P.,Salek, M.,Rappsilber, J.,Moores, C.A.,Salmon, E.D.,Musacchio, A. Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex Cell(Cambridge,Mass.), 133:427-, 2008 Cited by PubMed: 18455984 DOI: 10.1016/J.CELL.2008.03.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.88 Å)

Structure validation