2VDY
Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol
Summary for 2VDY
Entry DOI | 10.2210/pdb2vdy/pdb |
Related | 2VDX |
Descriptor | CORTICOSTEROID-BINDING GLOBULIN, (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione (3 entities in total) |
Functional Keywords | glycoprotein, lipid-binding, steroid-binding, disease mutation, corticosteroid binding globulin, transport protein, cbg, serpin, cleaved, secreted, cortisol, transport |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted: P08185 |
Total number of polymer chains | 2 |
Total formula weight | 84096.10 |
Authors | Zhou, A.,Wei, Z.,Read, R.J. (deposition date: 2007-10-13, release date: 2008-05-13, Last modification date: 2023-12-13) |
Primary citation | Zhou, A.,Wei, Z.,Stanley, P.L.,Read, R.J.,Stein, P.E.,Carrell, R.W. The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release. J.Mol.Biol., 380:244-, 2008 Cited by PubMed: 18513745DOI: 10.1016/J.JMB.2008.05.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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