2VDY

Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	CORTICOSTEROID-BINDING GLOBULIN	polymer	373	41685.6	2	UniProt (P08185) Pfam (PF00079)	HOMO SAPIENS (HUMAN)	CBG, TRANSCORTIN, SERPIN A6, HUMAN CORTICOSTEROID-BINDING GLOBULIN
2	C, D (A, B)	(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione	non-polymer		362.5	2	Chemie (HCY)
3	E, F (A, B)	water	water		18.0	165	Chemie (HOH)

Sequence modifications

A, B: 11 - 335 (UniProt: P08185)

PDB	External Database	Details
Thr 305	Asn 327	conflict

A, B: 350 - 383 (UniProt: P08185)
A, B: 336 - 349 (PDB: 2VDY)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83371.2
Non-Polymers*	Number of molecules	2
	Total formula weight	724.9
All*	Total formula weight	84096.1

*Water molecules are not included.