2SSP
LEUCINE-272-ALANINE URACIL-DNA GLYCOSYLASE BOUND TO ABASIC SITE-CONTAINING DNA
Summary for 2SSP
Entry DOI | 10.2210/pdb2ssp/pdb |
Descriptor | DNA (5'-D(*CP*TP*GP*TP*(AAB)P*AP*TP*CP*TP*T)-3'), DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*AP*G)-3'), PROTEIN (URACIL-DNA GLYCOSYLASE), ... (4 entities in total) |
Functional Keywords | dna glycosylase, dna base excision repair, uracil, dna, protein/dna, abasic site, protein-dna complex |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Mitochondrion. Isoform 2: Nucleus: P13051 |
Total number of polymer chains | 3 |
Total formula weight | 31794.21 |
Authors | Parikh, S.S.,Mol, C.D.,Slupphaug, G.,Bharati, S.,Krokan, H.E.,Tainer, J.A. (deposition date: 1999-04-28, release date: 1999-05-06, Last modification date: 2023-08-02) |
Primary citation | Parikh, S.S.,Mol, C.D.,Slupphaug, G.,Bharati, S.,Krokan, H.E.,Tainer, J.A. Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA. EMBO J., 17:5214-5226, 1998 Cited by PubMed: 9724657DOI: 10.1093/emboj/17.17.5214 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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