2SSP

LEUCINE-272-ALANINE URACIL-DNA GLYCOSYLASE BOUND TO ABASIC SITE-CONTAINING DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0004844	molecular_function	uracil DNA N-glycosylase activity
E	0006281	biological_process	DNA repair
E	0006284	biological_process	base-excision repair
E	0016799	molecular_function	hydrolase activity, hydrolyzing N-glycosyl compounds

Functional Information from PROSITE/UniProt

site_id	PS00130
Number of Residues	10
Details	U_DNA_GLYCOSYLASE Uracil-DNA glycosylase signature. KVVIlGQDPY

Chain	Residue	Details
E	LYS138-TYR147

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_03166, ECO:0000269|PubMed:9724657, ECO:0000312|PDB:1SSP

Chain	Residue	Details
E	ASP145

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:8900285, ECO:0000269|PubMed:9724657, ECO:0000312|PDB:1SSP, ECO:0000312|PDB:4SKN

Chain	Residue	Details
E	GLN144
E	PHE158
E	ASN204
E	HIS268

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site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:8900285, ECO:0000312|PDB:4SKN

Chain	Residue	Details
E	HIS148
E	SER169
E	SER247
E	SER270
E	SER273
E	ARG276

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
E	LYS286

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1eug

Chain	Residue	Details
E	ASP145
E	HIS268

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