2SHP
TYROSINE PHOSPHATASE SHP-2
Summary for 2SHP
Entry DOI | 10.2210/pdb2shp/pdb |
Descriptor | SHP-2, DODECANE-TRIMETHYLAMINE (3 entities in total) |
Functional Keywords | tyrosine phosphatase, insulin signaling, sh2 protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q06124 |
Total number of polymer chains | 2 |
Total formula weight | 120820.73 |
Authors | Hof, P.,Pluskey, S.,Dhe-Paganon, S.,Eck, M.J.,Shoelson, S.E. (deposition date: 1997-12-01, release date: 1999-02-16, Last modification date: 2024-04-03) |
Primary citation | Hof, P.,Pluskey, S.,Dhe-Paganon, S.,Eck, M.J.,Shoelson, S.E. Crystal structure of the tyrosine phosphatase SHP-2. Cell(Cambridge,Mass.), 92:441-450, 1998 Cited by PubMed: 9491886DOI: 10.1016/S0092-8674(00)80938-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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