Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE CAT A 1800 |
| Chain | Residue |
| A | THR356 |
| A | PHE420 |
| A | TRP423 |
| A | PRO429 |
| A | VAL435 |
| A | PHE438 |
| A | PHE469 |
| A | ILE472 |
| A | SER513 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CAT B 2800 |
| Chain | Residue |
| B | THR356 |
| B | PHE420 |
| B | TRP423 |
| B | PRO429 |
| B | SER430 |
| B | PRO432 |
| B | VAL435 |
| B | PHE438 |
| B | PHE469 |
| B | ILE472 |
| B | SER513 |
| B | MET516 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGigRTG |
| Chain | Residue | Details |
| A | VAL457-GLY467 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Phosphocysteine intermediate |
| Chain | Residue | Details |
| A | CYS459 | |
| B | CYS459 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP425 | |
| A | CYS459 | |
| A | GLN506 | |
| B | ASP425 | |
| B | CYS459 | |
| B | GLN506 | |
| Chain | Residue | Details |
| A | LYS2 | |
| B | LYS2 | |
| Chain | Residue | Details |
| A | TYR62 | |
| B | TYR62 | |
| Chain | Residue | Details |
| A | TYR66 | |
| B | TYR66 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| A | THR466 | |
| A | ARG465 | |
| A | CYS459 | |
| A | HIS458 | |
| A | GLU361 | |
| A | ASP425 | |
| site_id | CSA2 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| B | THR466 | |
| B | ARG465 | |
| B | CYS459 | |
| B | HIS458 | |
| B | GLU361 | |
| B | ASP425 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| A | ARG465 | |
| A | THR466 | |
| A | CYS459 | |
| A | ASP425 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| B | ARG465 | |
| B | THR466 | |
| B | CYS459 | |
| B | ASP425 | |
