Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
A | 0006470 | biological_process | protein dephosphorylation |
A | 0016311 | biological_process | dephosphorylation |
B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
B | 0006470 | biological_process | protein dephosphorylation |
B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE CAT A 1800 |
Chain | Residue |
A | THR356 |
A | PHE420 |
A | TRP423 |
A | PRO429 |
A | VAL435 |
A | PHE438 |
A | PHE469 |
A | ILE472 |
A | SER513 |
site_id | AC2 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE CAT B 2800 |
Chain | Residue |
B | THR356 |
B | PHE420 |
B | TRP423 |
B | PRO429 |
B | SER430 |
B | PRO432 |
B | VAL435 |
B | PHE438 |
B | PHE469 |
B | ILE472 |
B | SER513 |
B | MET516 |
Functional Information from PROSITE/UniProt
site_id | PS00383 |
Number of Residues | 11 |
Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGigRTG |
Chain | Residue | Details |
A | VAL457-GLY467 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Phosphocysteine intermediate |
Chain | Residue | Details |
A | CYS459 | |
B | CYS459 | |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | ASP425 | |
A | CYS459 | |
A | GLN506 | |
B | ASP425 | |
B | CYS459 | |
B | GLN506 | |
Chain | Residue | Details |
A | LYS2 | |
B | LYS2 | |
Chain | Residue | Details |
A | TYR62 | |
B | TYR62 | |
Chain | Residue | Details |
A | TYR66 | |
B | TYR66 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 6 |
Details | Annotated By Reference To The Literature 1ytw |
Chain | Residue | Details |
A | THR466 | |
A | ARG465 | |
A | CYS459 | |
A | HIS458 | |
A | GLU361 | |
A | ASP425 | |
site_id | CSA2 |
Number of Residues | 6 |
Details | Annotated By Reference To The Literature 1ytw |
Chain | Residue | Details |
B | THR466 | |
B | ARG465 | |
B | CYS459 | |
B | HIS458 | |
B | GLU361 | |
B | ASP425 | |
site_id | CSA3 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1ytw |
Chain | Residue | Details |
A | ARG465 | |
A | THR466 | |
A | CYS459 | |
A | ASP425 | |
site_id | CSA4 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1ytw |
Chain | Residue | Details |
B | ARG465 | |
B | THR466 | |
B | CYS459 | |
B | ASP425 | |