2SHP
TYROSINE PHOSPHATASE SHP-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | SHP-2 | polymer | 525 | 60181.9 | 2 | UniProt (Q06124) Pfam (PF00017) Pfam (PF00102) | Homo sapiens (human) | SYP, SHPTP-2 |
| 2 | C, D (A, B) | DODECANE-TRIMETHYLAMINE | non-polymer | 228.4 | 2 | Chemie (CAT) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 777 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 525 (UniProt: Q06124)
| PDB | External Database | Details |
|---|---|---|
| Lys 2 | Thr 2 | engineered mutation |
| Leu 41 | Phe 41 | engineered mutation |
| Ser 513 | Phe 513 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120363.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 456.9 | |
| All* | Total formula weight | 120820.7 |
