2R7G
Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain
Summary for 2R7G
Entry DOI | 10.2210/pdb2r7g/pdb |
Descriptor | Retinoblastoma-associated protein, Early E1A 32 kDa protein, SULFATE ION, ... (4 entities in total) |
Functional Keywords | retinoblastoma protein, e1a, e2f displacement, transcription repressor, cell cycle |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : P06400 Host nucleus : P03255 |
Total number of polymer chains | 5 |
Total formula weight | 85243.78 |
Authors | Liu, X.,Marmorstein, R. (deposition date: 2007-09-07, release date: 2007-10-02, Last modification date: 2024-02-21) |
Primary citation | Liu, X.,Marmorstein, R. Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor Genes Dev., 21:2711-2716, 2007 Cited by PubMed: 17974914DOI: 10.1101/gad.1590607 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.671 Å) |
Structure validation
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