2QJ2

A Mechanistic Basis for Converting a Receptor Tyrosine Kinase Agonist to an Antagonist

Summary for 2QJ2

Entry DOI	10.2210/pdb2qj2/pdb
Related	1BHT 1GMN 1GMO 1GP9 1NK1 2HGF 2QJ4
Descriptor	Hepatocyte growth factor, SULFATE ION (3 entities in total)
Functional Keywords	hgf/sf, hormone/growth factor, hormone
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	42702.72
Authors	Tolbert, W.D.,Daugherty, J.,Gao, C.-F.,Xe, Q.,Miranti, C.,Gherardi, E.,Vande Woude, G.,Xu, H.E. (deposition date: 2007-07-06, release date: 2007-09-18, Last modification date: 2023-08-30)
Primary citation	Tolbert, W.D.,Daugherty, J.,Gao, C.,Xie, Q.,Miranti, C.,Gherardi, E.,Vande Woude, G.,Xu, H.E. A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist Proc.Natl.Acad.Sci.Usa, 104:14592-14597, 2007 Cited by PubMed: 17804794 DOI: 10.1073/pnas.0704290104 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.81 Å)

Structure validation