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2QJ2

A Mechanistic Basis for Converting a Receptor Tyrosine Kinase Agonist to an Antagonist

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Hepatocyte growth factorpolymer18421159.22UniProt (P14210)
Pfam (PF00024)
Pfam (PF00051)
Homo sapiens (human)
2C, D, E, F
(A, B)
SULFATE IONnon-polymer96.14Chemie (SO4)
3G, H
(A, B)
waterwater18.0330Chemie (HOH)
Sequence modifications
A, B: 28 - 209 (UniProt: P14210)
PDBExternal DatabaseDetails
Gly 26-expression tag
Ser 27-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42318.5
Non-Polymers*Number of molecules4
Total formula weight384.3
All*Total formula weight42702.7
*Water molecules are not included.

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PDB entries from 2024-11-06

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