2Q72
Crystal Structure Analysis of LeuT complexed with L-leucine, sodium, and imipramine
Summary for 2Q72
| Entry DOI | 10.2210/pdb2q72/pdb |
| Related | 2A65 2Q6H 2QB4 2QEI |
| Descriptor | Transporter, octyl beta-D-glucopyranoside, SODIUM ION, ... (6 entities in total) |
| Functional Keywords | membrane protein, neurotransmitter sodium symporter, occluded, tricyclic antidepressant, transport protein |
| Biological source | Aquifex aeolicus |
| Total number of polymer chains | 1 |
| Total formula weight | 60277.25 |
| Authors | Singh, S.K.,Yamashita, A.,Gouaux, E. (deposition date: 2007-06-05, release date: 2007-08-21, Last modification date: 2023-08-30) |
| Primary citation | Singh, S.K.,Yamashita, A.,Gouaux, E. Antidepressant binding site in a bacterial homologue of neurotransmitter transporters. Nature, 448:952-956, 2007 Cited by PubMed: 17687333DOI: 10.1038/nature06038 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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