2Q72
Crystal Structure Analysis of LeuT complexed with L-leucine, sodium, and imipramine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transporter | polymer | 519 | 58077.4 | 1 | UniProt (O67854) Pfam (PF00209) | Aquifex aeolicus | |
| 2 | B, C, D, E, F (A) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 5 | Chemie (BOG) | |||
| 3 | G, H (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | I (A) | LEUCINE | non-polymer | 131.2 | 1 | Chemie (LEU) | |||
| 5 | J, K (A) | 3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE | non-polymer | 280.4 | 2 | Chemie (IXX) | |||
| 6 | L (A) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A: 1 - 513 (UniProt: O67854)
| PDB | External Database | Details |
|---|---|---|
| Gly 514 | - | cloning artifact |
| Thr 515 | - | cloning artifact |
| Leu 516 | - | cloning artifact |
| Val 517 | - | cloning artifact |
| Pro 518 | - | cloning artifact |
| Arg 519 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58077.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2199.8 | |
| All* | Total formula weight | 60277.3 |
