2QEI
Crystal structure analysis of LeuT complexed with L-alanine, sodium, and clomipramine
Summary for 2QEI
Entry DOI | 10.2210/pdb2qei/pdb |
Related | 2A65 2Q6H 2Q72 2QB4 |
Descriptor | Transporter, octyl beta-D-glucopyranoside, SODIUM ION, ... (6 entities in total) |
Functional Keywords | membrane protein, neurotransmitter sodium symporter, occluded, tricyclic antidepressant, inhibitor, transmembrane, transport, transport protein |
Biological source | Aquifex aeolicus |
Total number of polymer chains | 1 |
Total formula weight | 60304.06 |
Authors | Singh, S.K.,Yamashita, A.,Gouaux, E. (deposition date: 2007-06-25, release date: 2007-08-21, Last modification date: 2023-08-30) |
Primary citation | Singh, S.K.,Yamashita, A.,Gouaux, E. Antidepressant binding site in a bacterial homologue of neurotransmitter transporters. Nature, 448:952-956, 2007 Cited by PubMed: 17687333DOI: 10.1038/nature06038 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
Download full validation report