2PKS
Thrombin in complex with inhibitor
Summary for 2PKS
Entry DOI | 10.2210/pdb2pks/pdb |
Descriptor | Thrombin light chain, Thrombin heavy chain fragment, Hirudin, ... (7 entities in total) |
Functional Keywords | inhibitor complex, thrombin inhibitor, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 P00734 Secreted: P28504 |
Total number of polymer chains | 4 |
Total formula weight | 33554.39 |
Authors | |
Primary citation | Blomberg, D.,Fex, T.,Xue, Y.,Brickmann, K.,Kihlberg, J. Design, synthesis and biological evaluation of thrombin inhibitors based on a pyridine scaffold. Org.Biomol.Chem., 5:2599-2605, 2007 Cited by PubMed: 18019535DOI: 10.1039/b705344d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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