2PI8

Crystal structure of E. coli MltA with bound chitohexaose

Summary for 2PI8

• Entry DOI: 10.2210/pdb2pi8/pdb
• Related: 2AE0 2PIC 2PJJ
• Descriptor: Membrane-bound lytic murein transglycosylase A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: double-psi beta-barrel; protein-sugar complex; lytic transglycosylase, hydrolase
• Biological source: Escherichia coli
• Cellular location: Cell outer membrane; Lipid-anchor: P0A935
• Total number of polymer chains: 4
• Total formula weight: 160033.43

Authors

van Straaten, K.E.,Barends, T.R.M.,Dijkstra, B.W.,Thunnissen, A.M.W.H. (deposition date: 2007-04-13, release date: 2007-05-08, Last modification date: 2020-07-29)

• Primary citation: van Straaten, K.E.,Barends, T.R.M.,Dijkstra, B.W.,Thunnissen, A.M.W.H.; Structure of Escherichia coli Lytic transglycosylase MltA with bound chitohexaose: implications for peptidoglycan binding and cleavage; J.Biol.Chem., 282:21197-21205, 2007; PubMed: 17502382; DOI: 10.1074/jbc.M701818200

Experimental method

X-RAY DIFFRACTION (2.25 Å)