2PI8

Crystal structure of E. coli MltA with bound chitohexaose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Membrane-bound lytic murein transglycosylase A	polymer	345	38628.7	4	UniProt (P0A935) Pfam (PF03562) Pfam (PF06725) In PDB	Escherichia coli	Murein hydrolase A; Mlt38
2	E, F, G, H	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1237.2	4	In PDB GlyTouCan (G36414FS)
3	A, B, C, D	PHOSPHATE ION	non-polymer		95.0	6	Chemie (PO4)
4		water	water		18.0	198	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 345 (UniProt: P0A935)

PDB	External Database	Details
Mse 1	-	modified residue
Mse 77	Met 97	modified residue
Mse 87	Met 107	modified residue
Mse 123	Met 143	modified residue
Ser 131	Pro 151	conflict
Mse 154	Met 174	modified residue
Mse 159	Met 179	modified residue
Mse 206	Met 226	modified residue
Mse 208	Met 228	modified residue
Ile 272	Leu 292	conflict
Mse 293	Met 313	modified residue
Ala 308	Asp 328	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	154514.9
Branched	Number of molecules	4
	Total formula weight	4948.7
Non-Polymers*	Number of molecules	6
	Total formula weight	569.8
All*	Total formula weight	160033.4

*Water molecules are not included.