2PI0

Crystal Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-B enhancer

2PI0 の概要

• エントリーDOI: 10.2210/pdb2pi0/pdb
• 分子名称: PRDIII-I region of human interferon-B promoter strand 1, PRDIII-I region of human interferon-B promoter strand 2, Interferon regulatory factor 3, ... (4 entities in total)
• 機能のキーワード: interferon, protein-dna complex, transcription, transcription activator-dna complex, transcription activator/dna
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: 2PI0
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 73272.20

構造登録者

Escalante, C.R.,Nistal-Villan, E.,Leyi, S.,Garcia-Sastre, A.,Aggarwal, A.K. (登録日: 2007-04-12, 公開日: 2007-10-30, 最終更新日: 2023-08-30)

• 主引用文献: Escalante, C.R.,Nistal-Villan, E.,Shen, L.,Garcia-Sastre, A.,Aggarwal, A.K.; Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer.; Mol.Cell, 26:703-716, 2007; PubMed: 17560375; DOI: 10.1016/j.molcel.2007.04.022

実験手法

X-RAY DIFFRACTION (2.31 Å)