2PG5
Crystal Structure of Human Microsomal P450 2A6 N297Q
Summary for 2PG5
Entry DOI | 10.2210/pdb2pg5/pdb |
Related | 1Z10 1Z11 2FDU 2FDV 2FDW 2FDY 2PG6 2PG7 |
Descriptor | Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | cyp2a6, p450 2a6, p450, monooxygenases, drug metabolizing enzyme, heme, mutant, indole, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein: P11509 |
Total number of polymer chains | 4 |
Total formula weight | 221456.88 |
Authors | Sansen, S.,Hsu, M.H.,Stout, C.D.,Johnson, E.F. (deposition date: 2007-04-06, release date: 2007-07-24, Last modification date: 2023-08-30) |
Primary citation | Sansen, S.,Hsu, M.H.,Stout, C.D.,Johnson, E.F. Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants. Arch.Biochem.Biophys., 464:197-206, 2007 Cited by PubMed: 17540336DOI: 10.1016/j.abb.2007.04.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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