2PG5
Crystal Structure of Human Microsomal P450 2A6 N297Q
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Cytochrome P450 2A6 | polymer | 476 | 54685.7 | 4 | UniProt (P11509) Pfam (PF00067) UniProt (by SIFTS) (Q16696) In PDB | Homo sapiens (human) | CYPIIA6, Coumarin 7-hydroxylase, P450 IIA3, CYP2A3, P450I |
2 | A, B, C, D | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
3 | A, B, C, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
4 | water | water | 18.0 | 648 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 29 - 494 (UniProt: P11509)
PDB | External Database | Details |
---|---|---|
Met 23 | - | cloning artifact |
Ala 24 | - | cloning artifact |
Lys 25 | - | cloning artifact |
Lys 26 | - | cloning artifact |
Thr 27 | - | cloning artifact |
Ser 28 | - | cloning artifact |
Leu 160 | His 160 | variant |
Gln 297 | Asn 297 | engineered mutation |
His 495 | - | expression tag |
His 496 | - | expression tag |
His 497 | - | expression tag |
His 498 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 218742.7 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 2714.2 | |
All* | Total formula weight | 221456.9 |