2OO0

A structural insight into the inhibition of human and Leishmania donovani ornithine decarboxylases by 3-aminooxy-1-aminopropane

Summary for 2OO0

• Entry DOI: 10.2210/pdb2oo0/pdb
• Related: 1D7K 2ON3
• Descriptor: Ornithine decarboxylase, ACETATE ION, PYRIDOXAL-5'-PHOSPHATE, ... (6 entities in total)
• Functional Keywords: beta-alpha barrel, sheet, lyase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 105708.47

Authors

Dufe, V.T.,Ingner, D.,Khomutov, A.R.,Heby, O.,Persson, L.,Al-Karadaghi, S. (deposition date: 2007-01-25, release date: 2007-07-17, Last modification date: 2023-08-30)

• Primary citation: Dufe, V.T.,Ingner, D.,Heby, O.,Khomutov, A.R.,Persson, L.,Al-Karadaghi, S.; A structural insight into the inhibition of human and Leishmania donovani ornithine decarboxylases by 1-amino-oxy-3-aminopropane.; Biochem.J., 405:261-268, 2007; PubMed: 17407445; DOI: 10.1042/BJ20070188

Experimental method

X-RAY DIFFRACTION (1.9 Å)