2NQD
Crystal structure of cysteine protease inhibitor, chagasin, in complex with human cathepsin L
Summary for 2NQD
Entry DOI | 10.2210/pdb2nqd/pdb |
Related | 1CS8 1ICF 2H7W 2NNR |
Descriptor | Chagasin, Cathepsin L, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | chagasin-cathepsin l complex, three prong inhibition mode, hydrolase inhibitor-hydrolase complex, hydrolase inhibitor/hydrolase |
Biological source | Trypanosoma cruzi More |
Total number of polymer chains | 2 |
Total formula weight | 36694.87 |
Authors | Redzynia, I.,Bujacz, G.,Ljunggren, A.,Jaskolski, M.,Abrahamson, M. (deposition date: 2006-10-31, release date: 2007-07-24, Last modification date: 2023-10-25) |
Primary citation | Ljunggren, A.,Redzynia, I.,Alvarez-Fernandez, M.,Abrahamson, M.,Mort, J.S.,Krupa, J.C.,Jaskolski, M.,Bujacz, G. Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease J.Mol.Biol., 371:137-153, 2007 Cited by PubMed: 17561110DOI: 10.1016/j.jmb.2007.05.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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