2KM3
Structure of an intramolecular G-quadruplex containing a G.C.G.C tetrad formed by human telomeric variant CTAGGG repeats
Summary for 2KM3
Entry DOI | 10.2210/pdb2km3/pdb |
Related | 143D 1K8P 2AQY 2GKU 2JSK 2JSL 2JSM 2JSQ 2KF7 2KF8 |
Descriptor | DNA (5'-D(*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*G)-3') (1 entity in total) |
Functional Keywords | anticancer targets, ctaggg repeat, g-quadruplex, human telomere instability, dna |
Total number of polymer chains | 1 |
Total formula weight | 6938.46 |
Authors | Lim, K.W.,Alberti, P.,Guedin, A.,Lacroix, L.,Riou, J.F.,Royle, N.J.,Mergny, J.L.,Phan, A.T. (deposition date: 2009-07-17, release date: 2009-11-03, Last modification date: 2024-05-01) |
Primary citation | Lim, K.W.,Alberti, P.,Guedin, A.,Lacroix, L.,Riou, J.F.,Royle, N.J.,Mergny, J.L.,Phan, A.T. Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G.C.G.C tetrad Nucleic Acids Res., 37:6239-6248, 2009 Cited by PubMed: 19692585DOI: 10.1093/nar/gkp630 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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