2JLQ
Dengue virus 4 NS3 helicase structure, apo enzyme.
2JLQ の概要
エントリーDOI | 10.2210/pdb2jlq/pdb |
関連するPDBエントリー | 2JLR 2JLS 2JLU 2JLV 2JLW 2JLX 2JLY 2JLZ |
分子名称 | SERINE PROTEASE SUBUNIT NS3, CHLORIDE ION, GLYCEROL, ... (4 entities in total) |
機能のキーワード | ribonucleoprotein, nucleotide-binding, viral nucleoprotein, endoplasmic reticulum, helicase, protease, hydrolase, transferase, cleavage on pair of basic residues, multifunctional enzyme, transcription regulation, nucleotidyltransferase, ns3 helicase structure, virion, atpase, nucleus, membrane, secreted, atp-binding, rna-binding, flaviviruses, glycoprotein, rna-directed rna polymerase, rna replication, serine protease, envelope protein, dengue virus, metal-binding, transmembrane, transcription, phosphoprotein, capsid protein |
由来する生物種 | DENGUE VIRUS 4 |
細胞内の位置 | Capsid protein C: Virion (Potential). Peptide pr: Secreted (By similarity). Small envelope protein M: Virion membrane; Multi-pass membrane protein (By similarity). Envelope protein E: Virion membrane; Multi- pass membrane protein (By similarity). Non-structural protein 1: Secreted. Non-structural protein 2A-alpha: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Non-structural protein 2A: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Serine protease subunit NS2B: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Serine protease NS3: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Non-structural protein 4A: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Non-structural protein 4B: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). RNA-directed RNA polymerase NS5: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): Q2YHF0 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 51465.00 |
構造登録者 | Luo, D.H.,Xu, T.,Watson, R.P.,Becker, D.S.,Sampath, A.,Jahnke, W.,Yeong, S.S.,Wang, C.H.,Lim, S.P.,Vasudevan, S.G.,Lescar, J. (登録日: 2008-09-15, 公開日: 2008-11-25, 最終更新日: 2023-12-13) |
主引用文献 | Luo, D.,Xu, T.,Watson, R.P.,Scherer-Becker, D.,Sampath, A.,Jahnke, W.,Yeong, S.S.,Wang, C.H.,Lim, S.P.,Strongin, A.,Vasudevan, S.G.,Lescar, J. Insights Into RNA Unwinding and ATP Hydrolysis by the Flavivirus Ns3 Protein. Embo J., 27:3209-, 2008 Cited by PubMed: 19008861DOI: 10.1038/EMBOJ.2008.232 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.67 Å) |
構造検証レポート
検証レポート(詳細版)
をダウンロード
![ダウンロード](/newweb/media/icons/dl.png)