2JLQ

Dengue virus 4 NS3 helicase structure, apo enzyme.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004386	molecular_function	helicase activity
A	0005524	molecular_function	ATP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A1619

Chain	Residue
A	ARG387
A	THR408

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A1620

Chain	Residue
A	HOH2347
A	HOH2348
A	GLY320
A	SER321
A	ALA452
A	ASP482
A	LYS515
A	HOH2261
A	HOH2282

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00541

Chain	Residue	Details
A	LEU193

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Involved in NS3 ATPase and RTPase activities => ECO:0000250|UniProtKB:P14335

Chain	Residue	Details
A	ARG457
A	ARG460

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Cleavage; by autolysis => ECO:0000250|UniProtKB:P29990

Chain	Residue	Details
A	LYS618

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-acetyllysine; by host => ECO:0000250|UniProtKB:Q32ZE1

Chain	Residue	Details
A	LYS388

---