2JJT
Structure of human CD47 in complex with human signal regulatory protein (SIRP) alpha
Summary for 2JJT
Entry DOI | 10.2210/pdb2jjt/pdb |
Related | 2JJS 2UV3 2VSC |
Descriptor | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1, LEUKOCYTE SURFACE ANTIGEN CD47, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | signal regulatory protein alpha, immunoglobulin superfamily, transmembrane, phosphoprotein, paired receptor, polymorphism, glycoprotein, cell adhesion, pyrrolidone carboxylic acid, alternative splicing, immunoglobulin domain, sirp, cd47, sirpa, membrane, sh3-binding |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 4 |
Total formula weight | 58202.98 |
Authors | Hatherley, D.,Graham, S.C.,Turner, J.,Harlos, K.,Stuart, D.I.,Barclay, A.N. (deposition date: 2008-04-22, release date: 2008-08-05, Last modification date: 2023-12-13) |
Primary citation | Hatherley, D.,Graham, S.C.,Turner, J.,Harlos, K.,Stuart, D.I.,Barclay, A.N. Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47. Mol. Cell, 31:266-277, 2008 Cited by PubMed: 18657508DOI: 10.1016/j.molcel.2008.05.026 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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