2JJS

Structure of human CD47 in complex with human signal regulatory protein (SIRP) alpha

2JJS の概要

• エントリーDOI: 10.2210/pdb2jjs/pdb
• 関連するPDBエントリー: 2JJT 2UV3 2VSC
• 分子名称: TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1, LEUKOCYTE SURFACE ANTIGEN CD47, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: signal regulatory protein alpha, immunoglobulin superfamily, transmembrane, phosphoprotein, paired receptor, polymorphism, glycoprotein, cell adhesion, pyrrolidone carboxylic acid, alternative splicing, immunoglobulin domain, sirp, cd47, sirpa, membrane, sh3-binding
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 60487.25

構造登録者

Hatherley, D.,Graham, S.C.,Turner, J.,Harlos, K.,Stuart, D.I.,Barclay, A.N. (登録日: 2008-04-22, 公開日: 2008-08-05, 最終更新日: 2023-12-13)

• 主引用文献: Hatherley, D.,Graham, S.C.,Turner, J.,Harlos, K.,Stuart, D.I.,Barclay, A.N.; Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47.; Mol. Cell, 31:266-277, 2008; PubMed: 18657508; DOI: 10.1016/j.molcel.2008.05.026

実験手法

X-RAY DIFFRACTION (1.85 Å)