2JCS

Active site mutant of dNK from D. melanogaster with dTTP bound

2JCS の概要

• エントリーDOI: 10.2210/pdb2jcs/pdb
• 関連するPDBエントリー: 1J90 1OE0 1OT3 1ZM7 1ZMX
• 分子名称: DEOXYNUCLEOSIDE KINASE, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: kinase, transferase, atp-binding, dna synthesis, nucleotide- binding, deoxyribonucleoside kinase
• 由来する生物種: DROSOPHILA MELANOGASTER (FRUIT FLY)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 54798.31

構造登録者

Egeblad-Welin, L.,Sonntag, Y.,Eklund, H.,Munch-Petersen, B. (登録日: 2007-01-03, 公開日: 2007-02-27, 最終更新日: 2023-12-13)

• 主引用文献: Egeblad-Welin, L.,Sonntag, Y.,Eklund, H.,Munch-Petersen, B.; Functional Studies of Active-Site Mutants from Drosophila Melanogaster Deoxyribonucleoside Kinase. Investigations of the Putative Catalytic Glutamate- Arginine Pair and of Residues Responsible for Substrate Specificity.; FEBS J., 274:1542-, 2007; PubMed: 17302737; DOI: 10.1111/J.1742-4658.2007.05701.X

実験手法

X-RAY DIFFRACTION (2.5 Å)