2J9K
Atomic-resolution Crystal Structure of Chemically-Synthesized HIV-1 Protease Complexed with Inhibitor MVT-101
Summary for 2J9K
Entry DOI | 10.2210/pdb2j9k/pdb |
Related | 2J9J |
Related PRD ID | PRD_000398 |
Descriptor | PROTEASE, N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, SULFATE ION, ... (6 entities in total) |
Functional Keywords | protease, hydrolase-hydrolase inhibitor complex, aspartyl protease, human immunodeficiency virus 1, hydrolase/hydrolase inhibitor |
Biological source | HUMAN IMMUNODEFICIENCY VIRUS 1 |
Total number of polymer chains | 2 |
Total formula weight | 23223.99 |
Authors | Malito, E.,Shen, Y.,Johnson, E.C.B.,Tang, W.J. (deposition date: 2006-11-11, release date: 2007-08-28, Last modification date: 2023-12-13) |
Primary citation | Johnson, E.C.B.,Malito, E.,Shen, Y.,Pentelute, B.,Rich, D.,Florian, J.,Tang, W.J.,Kent, S.B.H. Insights from Atomic-Resolution X-Ray Structures of Chemically Synthesized HIV-1 Protease in Complex with Inhibitors. J.Mol.Biol., 373:573-, 2007 Cited by PubMed: 17869270DOI: 10.1016/J.JMB.2007.07.054 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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