Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE 2NC A 0 |
| Chain | Residue |
| A | ARG8 |
| A | ILE50 |
| A | VAL82 |
| A | HOH2011 |
| A | HOH2028 |
| A | HOH2031 |
| A | HOH2079 |
| A | HOH2080 |
| A | HOH2081 |
| B | ARG8 |
| B | ASP25 |
| A | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | GLY48 |
| B | GLY49 |
| B | VAL82 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1105 |
| Chain | Residue |
| A | PRO1 |
| A | ARG57 |
| A | HIS69 |
| A | HOH2058 |
| B | HOH2073 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1106 |
| Chain | Residue |
| A | GLY73 |
| A | THR74 |
| A | ASN88 |
| A | HOH2029 |
| A | HOH2070 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 1107 |
| Chain | Residue |
| A | LYS7 |
| A | ARG8 |
| A | HOH2010 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 1108 |
| Chain | Residue |
| A | LYS55 |
| A | ARG57 |
| A | GLY68 |
| A | HOH2038 |
| A | HOH2052 |
| A | HOH2056 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1109 |
| Chain | Residue |
| A | PHE99 |
| A | HOH2060 |
| A | HOH2078 |
| B | NLE46 |
| B | PHE53 |
| B | LYS55 |
| B | HIS69 |
| B | SO41107 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1110 |
| Chain | Residue |
| A | VAL11 |
| A | THR12 |
| A | SLZ41 |
| A | TRP42 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1105 |
| Chain | Residue |
| A | ARG14 |
| A | HOH2016 |
| B | ARG14 |
| B | GLY17 |
| B | PRO63 |
| B | HOH2055 |
| B | HOH2075 |
| B | HOH2076 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1106 |
| Chain | Residue |
| A | HIS69 |
| A | LYS70 |
| A | HOH2060 |
| B | PRO1 |
| B | LYS55 |
| B | SO41107 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1107 |
| Chain | Residue |
| A | HIS69 |
| A | GOL1109 |
| A | HOH2059 |
| B | PRO1 |
| B | HIS69 |
| B | SO41106 |
| B | HOH2074 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 1108 |
| Chain | Residue |
| B | GLY73 |
| B | THR74 |
| B | ASN88 |
| B | GLN92 |
| B | HOH2062 |
| B | HOH2066 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ACT B 1109 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 1110 |
| Chain | Residue |
| A | LYS55 |
| A | LYS70 |
| B | LYS70 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE99 | |
