2J24

The functional role of the conserved active site proline of triosephosphate isomerase

Summary for 2J24

Entry DOI	10.2210/pdb2j24/pdb
Related	1AG1 1DKW 1IIG 1IIH 1KV5 1ML1 1MSS 1MTM 1TPD 1TPE 1TPF 1TRD 1TRI 1TSI 1TTI 1TTJ 3TIM 4TIM 5TIM 6TIM
Descriptor	TRIOSEPHOSPHATE ISOMERASE, GLYCOSOMAL (2 entities in total)
Functional Keywords	isomerase, protein engineering, fatty acid biosynthesis, gluconeogenesis, lipid synthesis, pentose shunt, point mutation, loop7, glycosome, tim-barrel
Biological source	TRYPANOSOMA BRUCEI BRUCEI
Cellular location	Glycosome: P04789
Total number of polymer chains	2
Total formula weight	53679.59
Authors	Casteleijn, M.G.,Alahuhta, M.,Groebel, K.,El-Sayed, I.,Augustyns, K.,Lambeir, A.M.,Neubauer, P.,Wierenga, R.K. (deposition date: 2006-08-16, release date: 2007-01-02, Last modification date: 2023-12-13)
Primary citation	Casteleijn, M.G.,Alahuhta, M.,Groebel, K.,El-Sayed, I.,Augustyns, K.,Lambeir, A.M.,Neubauer, P.,Wierenga, R.K. Functional Role of the Conserved Active Site Proline of Triosephosphate Isomerase. Biochemistry, 45:15483-, 2006 Cited by PubMed: 17176070 DOI: 10.1021/BI061683J PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation