2IM1

Crystal structure of poliovirus polymerase complexed with CTP and Mn2+

2IM1 の概要

• エントリーDOI: 10.2210/pdb2im1/pdb
• 関連するPDBエントリー: 1RA6 1RA7 2ILY 2ILZ 2IM0 2IM2 2IM3
• 分子名称: poliovirus polymerase, MANGANESE (II) ION, SODIUM ION, ... (6 entities in total)
• 機能のキーワード: nucleotidyltransferase, poliovirus, 3d, rna-dependent, polymerase, ctp, stabilization, transferase
• 由来する生物種: Human poliovirus 1
• 細胞内の位置: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03300
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 53959.08

構造登録者

Thompson, A.A.,Peersen, O.B. (登録日: 2006-10-03, 公開日: 2006-12-12, 最終更新日: 2023-08-30)

• 主引用文献: Thompson, A.A.,Albertini, R.A.,Peersen, O.B.; Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.; J.Mol.Biol., 366:1459-1474, 2007; PubMed: 17223130; DOI: 10.1016/j.jmb.2006.11.070

実験手法

X-RAY DIFFRACTION (2.5 Å)