2IH2

Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 5-methylpyrimidin-2(1H)-one at the target base partner position

Summary for 2IH2

• Entry DOI: 10.2210/pdb2ih2/pdb
• Related: 1AQI 1AQJ 1G38 2ADM 2IBS 2IBT 2IH4 2IH5
• Descriptor: 5'-D(*GP*TP*TP*CP*GP*AP*TP*GP*TP*C)-3', 5'-D(*GP*AP*CP*AP*(5PY)P*CP*GP*(6MA)P*AP*C)-3', Modification methylase TaqI, ... (6 entities in total)
• Functional Keywords: dna, dna methyltransferase, target base partner, 5-methylpyrimidin-2(1h)-one, base flipping, nucleotide flipping, transferase-dna complex, transferase/dna
• Biological source: Thermus aquaticus; More
• Total number of polymer chains: 6
• Total formula weight: 109149.71

Authors

Lenz, T.,Scheidig, A.J.,Weinhold, E. (deposition date: 2006-09-25, release date: 2007-11-13, Last modification date: 2023-08-30)

• Primary citation: Lenz, T.,Scheidig, A.J.,Weinhold, E.; Influence of the target base partner on the methylation rate of the adenine-specific DNA methyltransferase M.TaqI; To be Published,

Experimental method

X-RAY DIFFRACTION (1.61 Å)