2HKA
Crystal structure of bovine NPC2 and cholesterol sulfate complex
Summary for 2HKA
Entry DOI | 10.2210/pdb2hka/pdb |
Descriptor | Epididymal secretory protein E1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... (7 entities in total) |
Functional Keywords | beta barrel, lipid binding protein |
Biological source | Bos taurus (cattle) |
Cellular location | Secreted: P79345 |
Total number of polymer chains | 3 |
Total formula weight | 46321.93 |
Authors | Xu, S.,Gu, L.,Benoff, B.,Stock, A.M. (deposition date: 2006-07-03, release date: 2007-06-26, Last modification date: 2023-08-30) |
Primary citation | Xu, S.,Benoff, B.,Liou, H.-L.,Lobel, P.,Stock, A.M. Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease J.Biol.Chem., 282:23525-23531, 2007 Cited by PubMed: 17573352DOI: 10.1074/jbc.M703848200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
Download full validation report