2HKA
Crystal structure of bovine NPC2 and cholesterol sulfate complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Epididymal secretory protein E1 | polymer | 130 | 14632.7 | 3 | UniProt (P79345) Pfam (PF02221) | Bos taurus (cattle) | Niemann Pick type C2 protein homolog, NPC2, EPV20 |
| 2 | D, G, O (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 3 | E, F, H, I, J... (A, B, C) | ACETATE ION | non-polymer | 59.0 | 6 | Chemie (ACT) | |||
| 4 | K, L, Q (B, C) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | M, R (B, C) | CHOLEST-5-EN-3-YL HYDROGEN SULFATE | non-polymer | 466.7 | 2 | Chemie (C3S) | |||
| 6 | N, S (B, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | T, U, V (A, B, C) | water | water | 18.0 | 371 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 43898.2 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2423.7 | |
| All* | Total formula weight | 46321.9 |
