2FTO
Y94F mutant of thymidylate synthase bound to thymidine-5'-phosphate and 10-propargyl-5,8-dideazafolid acid
Summary for 2FTO
| Entry DOI | 10.2210/pdb2fto/pdb |
| Related | 2ftn 2ftq |
| Descriptor | Thymidylate synthase, PHOSPHATE ION, THYMIDINE-5'-PHOSPHATE, ... (5 entities in total) |
| Functional Keywords | methyltransferase, transferase |
| Biological source | Escherichia coli |
| Cellular location | Cytoplasm : P0A884 |
| Total number of polymer chains | 1 |
| Total formula weight | 31533.28 |
| Authors | Roberts, S.A.,Montfort, W.R. (deposition date: 2006-01-24, release date: 2006-05-02, Last modification date: 2021-10-20) |
| Primary citation | Roberts, S.A.,Hyatt, D.C.,Honts, J.E.,Changchien, L.,Maley, G.F.,Maley, F.,Montfort, W.R. Structure of the Y94F mutant of Escherichia coli thymidylate synthase. ACTA CRYSTALLOGR.,SECT.F, 62:840-843, 2006 Cited by PubMed: 16946460DOI: 10.1107/S1744309106029691 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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