2FLP
Binary complex of the catalytic core of human DNA polymerase iota with DNA (template G)
Summary for 2FLP
Entry DOI | 10.2210/pdb2flp/pdb |
Related | 1T3N 2ALZ 2FLL 2FLN |
Descriptor | DNA template strand, DNA primer strand, DNA polymerase iota, ... (4 entities in total) |
Functional Keywords | dna polymerase, lesion bypass, y-family, binary complex, template g, replication-dna complex, replication/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9UNA4 |
Total number of polymer chains | 3 |
Total formula weight | 52474.94 |
Authors | Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. (deposition date: 2006-01-06, release date: 2006-12-05, Last modification date: 2024-04-03) |
Primary citation | Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure, 14:749-755, 2006 Cited by PubMed: 16615915DOI: 10.1016/j.str.2006.01.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report