2FCC
Crystal Structure of T4 Pyrimidine Dimer Glycosylase (T4-Pdg) Covalently Complexed with a DNA Substrate Containing Abasic Site
Summary for 2FCC
Entry DOI | 10.2210/pdb2fcc/pdb |
Descriptor | DNA (5'-D(*CP*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*(BRU)P*(BRU)P*CP*AP*(BRU)P*CP*CP*(BRU)P*GP*G)-3'), Endonuclease V, ... (6 entities in total) |
Functional Keywords | t4-pdg, pyrimidine dimer, dna repair, endonuclease, enzyme-dna complex, covalent intermediate, hydrolase |
Biological source | Enterobacteria phage T4 More |
Total number of polymer chains | 6 |
Total formula weight | 48486.23 |
Authors | Golan, G.,Zharkov, D.O.,Fernandes, A.S.,Dodson, M.L.,McCullough, A.K.,Grollman, A.P.,Lloyd, R.S.,Shoham, G. (deposition date: 2005-12-12, release date: 2006-10-03, Last modification date: 2023-08-30) |
Primary citation | Golan, G.,Zharkov, D.O.,Grollman, A.P.,Dodson, M.L.,McCullough, A.K.,Lloyd, R.S.,Shoham, G. Structure of T4 Pyrimidine Dimer Glycosylase in a Reduced Imine Covalent Complex with Abasic Site-containing DNA. J.Mol.Biol., 362:241-258, 2006 Cited by PubMed: 16916523DOI: 10.1016/j.jmb.2006.06.059 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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